منابع مشابه
Iron refractory iron deficiency anemia.
Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6 gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an essential role in down-regulating hepcidin, the key regulator of iron homeostasis. Hallmarks of this disease are microcytic hypochromic anemia, low transferrin saturation and normal/high serum hepcidin va...
متن کاملIron-Refractory Iron Deficiency Anemia
Iron is essential for life because it is indispensable for several biological reactions, such as oxygen transport, DNA synthesis, and cell proliferation. Over the past few years, our understanding of iron metabolism and its regulation has changed dramatically. New disorders of iron metabolism have emerged, and the role of iron as a cofactor in other disorders has begun to be recognized. The stu...
متن کاملAnemia, Iron Deficiency, and Iron Deficiency Anemia
Anemia is one of the most widespread public health problems, especially in developing countries, and has important health and welfare, social, and economic consequences. These include impaired cognitive development, reduced physical work capacity, and in severe cases increased risk of mortality, particularly during the perinatal period. There is also evidence that anemia may result in reduced g...
متن کاملRefractory anemia with ring sideroblasts masked by iron deficiency anemia.
A 84-year-old woman with a long-standing history of progressive exertional dyspnea and fatigue was assessed for concomitant anemia. She also had coronary artery disease, chronic obstructive pulmonary disease, hypertension, and gout. Her hemoglobin was 109 g/L with a mean corpuscular volume of 76.1 fL and red blood cell distribution width (RDW) at 19.4%. White cell count including differential a...
متن کامل55 Cases of Iron Deficiency Anemia
55 cases of iron SUMMARY deficiency anemia were hosThis pitalized type at of anemia Bahrami was Hospital found in to be one the year. most Our frequent study cause showed of that anemia in in infants infants, in malnutriIran. tion older· was age the other main causes cause such of as anemia, GI while leeding,in ethiologie parasitosis of and the chronic disease. Most infection infants were wit...
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ژورنال
عنوان ژورنال: Turkish Journal of Hematology
سال: 2015
ISSN: 1300-7777
DOI: 10.4274/tjh.2014.0288